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[BOOKS ET AL.] ENVIRONMENTAL ART: Hejira in a Jetta
Horgan's often humorous narrative of her journey to several monumental earthworks from the 1970s and 1980s interweaves her personal observations and responses with art history and theory. Author: Mary Parrish

[BOOKS ET AL.] BROWSINGS
Author: Mary Parrish

[BOOKS ET AL.] THEATER: To Make Aire Dance
This history play on the emergence of science in the 17th century and the growth of public scientific demonstrations and debate pits the philosopher Hobbes against a group led by Robert Hooke and Robert Boyle. Author: Caroline Ash

[EDUCATION FORUM] THE PIPELINE: Science Faculty with Education Specialties
Career dynamics for science faculty with interests in education point the way for developing this nascent career specialty. Authors: S. D. Bush, N. J. Pelaez, J. A. Rudd, M. T. Stevens, K. D. Tanner, K. S. Williams

[POLICY FORUM] RESEARCH FUNDING: Politics and Funding in the U.S. Public Biomedical R&D System
Research grant allocations can be affected by appropriations committee representation. Authors: Deepak Hegde, David C. Mowery

[PERSPECTIVES] EVOLUTION: Who's Your Daddy?
The male-only nest care system of some birds may have its evolutionary origins in theropod dinosaur behavior. Author: Richard O. Prum

[PERSPECTIVES] COMPUTER SCIENCE: The Ethical Frontiers of Robotics
The use of robots to care for the young and the old, and as autonomous agents on the battlefield, raises ethical issues. Author: Noel Sharkey

[PERSPECTIVES] MATERIALS SCIENCE: Now You See Them
Can new results on calcium carbonate nucleation be reconciled with classical nucleation theory? Authors: Fiona C. Meldrum, Richard P. Sear

[PERSPECTIVES] DEVELOPMENTAL BIOLOGY: From Genetic Association to Genetic Switch
Human genetic studies have led to the identification of a transcriptional regulator that could serve as a therapeutic target for adult hemoglobin disorders. Author: Alan M. Michelson

[PERSPECTIVES] TRANSCRIPTION: Gene Expression--Where to Start?
Transcription just got noisier with the discovery of short RNAs that are synthesized at or near DNA regions that also initiate full-length RNAs. Author: Stephen Buratowski

[AAAS AFFAIRS] AAAS News and Notes
A monthly roundup of recent news and projects of Science's publisher, the American Association for the Advancement of Science. Author:

[REVIEWS] Nuclear Reprogramming in Cells
Authors: J. B. Gurdon, D. A. Melton

[REPORTS] Matching Glass-Forming Ability with the Density of the Amorphous Phase
The change in density during crystallization predicts which copper-zirconium alloys can most easily form a metallic glass. Authors: Y. Li, Q. Guo, J. A. Kalb, C. V. Thompson

[REPORTS] Stable Prenucleation Calcium Carbonate Clusters
Even unsaturated solutions contain stable neutral clusters of calcium carbonate, which may aid in crystallization and biomineralization. Authors: Denis Gebauer, Antje Völkel, Helmut Cölfen

[REPORTS] Shock-Wave Exploration of the High-Pressure Phases of Carbon
A magnetically driven plate shocks diamond to extreme pressures and temperatures, allowing resolution of its melting regime and a possible higher-pressure phase. Authors: M. D. Knudson, M. P. Desjarlais, D. H. Dolan

[REPORTS] Avian Paternal Care Had Dinosaur Origin
The large egg clutches of troodontid and oviraptor dinosaurs and evidence that fossils of brooding dinosaurs were males shows that paternal care was ancestral to birds. Authors: David J. Varricchio, Jason R. Moore, Gregory M. Erickson, Mark A. Norell, Frankie D. Jackson, John J. Borkowski

[REPORTS] Orbital Identification of Carbonate-Bearing Rocks on Mars
Despite widespread acidic weathering on Mars, detection of carbonatebearing rocks indicates that nonacidic waters existed in the past. Authors: Bethany L. Ehlmann, John F. Mustard, Scott L. Murchie, Francois Poulet, Janice L. Bishop, Adrian J. Brown, Wendy M. Calvin, Roger N. Clark, David J. Des Marais, Ralph E. Milliken, Leah H. Roach, Ted L. Roush, Gregg A. Swayze, James J. Wray

[REPORTS] The Circadian Clock in Arabidopsis Roots Is a Simplified Slave Version of the Clock in Shoots
A simpler plant circadian clock, which normally has three interlocking feedback loops, is used in the roots, with one feedback loop regulating only a few genes. Authors: Allan B. James, José A. Monreal, Gillian A. Nimmo, Ciarán L. Kelly, Pawel Herzyk, Gareth I. Jenkins, Hugh G. Nimmo

[REPORTS] A Conserved Molecular Framework for Compound Leaf Development
A family of transcription factors controls the formation of leaflets and lobes in complex leaves in distantly related plants by controlling outgrowth from leaf margins. Authors: Thomas Blein, Amada Pulido, Aurélie Vialette-Guiraud, Krisztina Nikovics, Halima Morin, Angela Hay, Ida Elisabeth Johansen, Miltos Tsiantis, Patrick Laufs

[REPORTS] Human Fetal Hemoglobin Expression Is Regulated by the Developmental Stage-Specific Repressor BCL11A
A way to reactivate a fetal form of Authors: Vijay G. Sankaran, Tobias F. Menne, Jian Xu, Thomas E. Akie, Guillaume Lettre, Ben Van Handel, Hanna K. A. Mikkola, Joel N. Hirschhorn, Alan B. Cantor, Stuart H. Orkin

[REPORTS] CRISPR Interference Limits Horizontal Gene Transfer in Staphylococci by Targeting DNA
The small CRISPR RNAs in Staphylococci bacteria that protect against phage infection are complementary to foreign phage DNA and target it for destruction. Authors: Luciano A. Marraffini, Erik J. Sontheimer

[REPORTS] Nascent RNA Sequencing Reveals Widespread Pausing and Divergent Initiation at Human Promoters
RNA sequencing identifies antisense transcription immediately upstream of genes with transcriptionally engaged RNA polymerase. Authors: Leighton J. Core, Joshua J. Waterfall, John T. Lis

[REPORTS] Divergent Transcription from Active Promoters
Active genes produce promoter-localized sense and antisense short RNAs, suggesting frequent transcription by divergently oriented RNA polymerase II complexes at mammalian promoters. Authors: Amy C. Seila, J. Mauro Calabrese, Stuart S. Levine, Gene W. Yeo, Peter B. Rahl, Ryan A. Flynn, Richard A. Young, Phillip A. Sharp

[REPORTS] RNA Exosome Depletion Reveals Transcription Upstream of Active Human Promoters
Highly unstable transcripts exist upstream of active human promoters. Authors: Pascal Preker, Jesper Nielsen, Susanne Kammler, Søren Lykke-Andersen, Marianne S. Christensen, Christophe K. Mapendano, Mikkel H. Schierup, Torben Heick Jensen

[REPORTS] The Antisense Transcriptomes of Human Cells
The abundance and nonrandom genomic origin of antisense transcripts in human cells suggest that these RNAs are an important feature of gene regulation. Authors: Yiping He, Bert Vogelstein, Victor E. Velculescu, Nickolas Papadopoulos, Kenneth W. Kinzler

[REPORTS] Label-Free Biomedical Imaging with High Sensitivity by Stimulated Raman Scattering Microscopy
Three-dimensional imaging based on stimulated Raman scattering can detect lipids in living cells and monitor the movement of drugs through the skin. Authors: Christian W. Freudiger, Wei Min, Brian G. Saar, Sijia Lu, Gary R. Holtom, Chengwei He, Jason C. Tsai, Jing X. Kang, X. Sunney Xie

[REPORTS] Leukemic Cells Create Bone Marrow Niches That Disrupt the Behavior of Normal Hematopoietic Progenitor Cells
Cancerous immune cells create abnormal microenvironments in bone marrow that attract normal immune precursor cells, disrupting their function and exacerbating disease. Authors: Angela Colmone, Maria Amorim, Andrea L. Pontier, Sheng Wang, Elizabeth Jablonski, Dorothy A. Sipkins

[REPORTS] Representation of Geometric Borders in the Entorhinal Cortex
A previously unknown cell type in the brain's cortex encodes geometric boundaries of the nearby environment, perhaps providing a frame of reference. Authors: Trygve Solstad, Charlotte N. Boccara, Emilio Kropff, May-Britt Moser, Edvard I. Moser

[NEWS] PARTICLE PHYSICS: Sotto Voce, LHC Repair Plan Points to Weaknesses in Original Design
Officials at CERN, the European particle physics lab near Geneva, Switzerland, issued a four-page report last week tersely describing how they plan to get the Large Hadron Collider (LHC), the world's biggest particle smasher, working again after its 19 September breakdown. Author: Adrian Cho

[NEWS] BIOSECURITY: How Kansas Nabbed the New Bio- and Agro-Defense Lab
Last week, the U.S. Department of Homeland Security selected Kansas State University in Manhattan as its preferred site for a $450 million facility to replace the aging Plum Island Animal Disease Center off Long Island, New York. Author: Yudhijit Bhattacharjee

[NEWS] NATIONAL INSTITUTES OF HEALTH: Researchers Could Face More Scrutiny of Outside Income
As controversy escalates about researchers who allegedly broke rules on reporting income from drug companies, U.S. National Institutes of Health officials outlined plans last week to tighten federal conflict-of-interest regulations for NIH grantees within the next 6 to 12 months. Authors: Jocelyn Kaiser, Lila Guterman

[NEWS] MALARIA: Vaccine Comes Another Step Closer
The most advanced candidate vaccine for malaria has cleared another major hurdle and is now ready for its last and biggest test: a phase III trial of 12,000 to 16,000 children at 11 locations in seven African countries. Author: Martin Enserink

[NEWS] SCIENCE POLICY: Biosummit Seeks to Draw Obama's Attention to the Life Sciences
A group of scientists met last week in Washington, D.C., at a "Biosummit," part of a new campaign to focus public attention on the importance of the life sciences. Author: Eliot Marshall

[NEWS FOCUS] ECONOMICS: Crazy Money
Humans aren't rational, as the recent economic crisis shows. So why should financial theories assume that they are? Author: Chelsea Wald

[NEWS FOCUS] OCEANOGRAPHY: FerryBoxes Begin to Make Waves
European researchers have enlisted a fleet of ferries to inexpensively gather valuable data about the region's waters. Author: Claire Ainsworth

[NEWS FOCUS] OCEANOGRAPHY: Logbooks Record Weather's History
Researchers are using old maritime logbooks to reconstruct a record of the weather stretching back to the 17th century. Author: Claire Ainsworth

[NEWS FOCUS] ECOLOGY: When Juniper and Woody Plants Invade, Water May Retreat
Dense plants are taking over grasslands in many areas; researchers in the U.S. Southwest are studying how they tap into water supplies--and how to keep them in check. Author: Michael Tennesen

[LETTERS] Testing the Limits of "Concrete" and "Generic"
Author: Jean-Christophe Mourrat

[LETTERS] "Concrete" Examples a Fraction Too Abstract
Author: Louis J. Cutrona Jr.

[LETTERS] Concrete Examples Must Jibe with Experience
Authors: Stephen K. Reed;, Jennifer A. Kaminski, Vladimir M. Sloutsky, Andrew F. Heckler

[LETTERS] Gene Regulation in Evolution: A History
Author: John W. Grula

[TECHNICAL COMMENT] Comment on “An Association Between the Kinship and Fertility of Human Couples”
Authors: Rodrigo Labouriau, António Amorim

[TECHNICAL RESPONSE] Response to Comments on “An Association Between the Kinship and Fertility of Human Couples”
Authors: Agnar Helgason, Snæbjörn Pálsson, Daníel F. Guðbjartsson, Þórður Kristjánsson, Kári Stefánsson

[BOOKS ET AL.] MEDICINE: Yes We Can! Choose Science in Autism
Presenting a strong case against claims that autism is caused by childhood vaccines, Offit also discusses why the antivaccine movement has attracted support. Author: Catherine Lord

[BOOKS ET AL.] NEUROSCIENCE: The Emerging Nature of Nurture
Stiles draws on the findings of the past two decades to provide an inclusive and accessible account of the complexities and dynamism of brain development. Author: Mriganka Sur