A nanostructured gate dielectric may have addressed the most significant obstacle to expanding the use of organic semiconductors for thin-film transistors. The structure, composed of a fluoropolymer layer followed by a nanolaminate made from two metal oxide materials, serves as gate dielectric and protects the organic semiconductor – which had previously been vulnerable to damage from the ambient environment.
By analyzing immune cells of children who came to the emergency department with flu symptoms, researchers found that the suite of genes these early-response cells expressed was shaped by factors such as age and previous exposures to viruses. Better understanding how early infections influence long-term immune response has implications for the diagnosis and treatment of young patients who suffer from acute respiratory tract infections.
Microscopic yeast have been wreaking havoc in hospitals around the world — creeping into catheters, ventilator tubes, and IV lines — and causing deadly invasive infection. One culprit species, Candida auris, is resistant to many antifungals, meaning once a person is infected, there are limited treatment options. But researchers have now confirmed a new drug compound kills drug-resistant C. auris, both in the laboratory and in a mouse model that mimics human infection.
Researchers have discovered a previously unknown warning system that contributes to the body’s immune system. Mitochondria in the white blood cells secrete a web of DNA fibers that raises the alarm. The results may lead to increased knowledge about autoinflammatory diseases and cancer.
Current therapies for Parkinson’s disease are mainly of a replacement type and pose problems in the long term, so the challenge is to establish an early diagnosis and develop neuroprotective and neurorestorative therapies that will allow the symptoms of the disease to be slowed down or even reversed. Researcher have now documented the regenerative, neuroprotective effect of two neurotrophic factors when they are applied in a combined way.