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Global vaccine injury system needed to improve public health

A global vaccine injury compensation system administered through the World Health Organization would address the global public health issue of vaccine injuries, experts argue.

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Nematode resistance in soybeans beneficial even at low rates of infestation

Soybeans with resistance to soybean cyst nematodes seem to have a yield advantage compared to susceptible varieties when SCN is present. Until now, scientists did not know what level of SCN infestation is needed to achieve the yield advantage. A new study shows that SCN resistance from the soybean accession PI 88788 offers yield advantages even at very low infestation rates.

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Gene mutations cause leukemia, but which ones?

New research sought to better understand one ‘typo’ in a standard leukemia assay, or test. The study, however, encountered a new problem: an issue with the model system itself.

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Contact tracing and targeted insecticide spraying can curb dengue outbreaks

Contact tracing — a process of identifying everyone who has come into contact with those infected by a particular disease — combined with targeted, indoor spraying of insecticide can greatly reduce the spread of the mosquito-borne dengue virus, finds a study.

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Air pollution may have masked mid-20th Century sea ice loss

Humans may have been altering Arctic sea ice longer than previously thought, according to researchers studying the effects of air pollution on sea ice growth in the mid-20th Century.

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Vast luminous nebula poses a cosmic mystery

Astronomers have found an enormous, glowing blob of gas in the distant universe, with no obvious source of power for the light it is emitting. Called an ‘enormous Lyman-alpha nebula’ (ELAN), it is the brightest and among the largest of these rare objects, only a handful of which have been observed.

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New link found between sex and viruses

Sexual reproduction and viral infections both rely on a functionally identical protein, according to new research. The protein enables the fusion of two cells, such as a sperm cell and egg cell, or the fusion of a virus with a cell membrane. The discovery suggests that the protein evolved early in the history of life on Earth, and new details about the protein’s function could help fight parasitic diseases such as malaria.

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Almost 4 decades later, mini eyeless catfish gets a name

Discovered in a 1978-79 expedition, a pale, eyeless catfish that doesn’t even measure an inch long is now known as Micromyzon orinoco, for the South American river in which it was discovered.

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Why is pancreatic cancer so hard to treat? Stroma provides new clues

Why are pancreatic tumors so resistant to treatment? One reason is that the ‘wound’-like tissue that surrounds the tumors, called stroma, is so dense, likely preventing cancer-killing drugs from reaching the tumor. A team has now discovered heterogeneity in the fibroblast portion of the stroma, opening up the possibility of targeted treatment.

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Alternate Cyclization Cascade Initiated by Substrate Isomer in Multiproduct Terpene Synthase from Medicago truncatula

TOC Graphic

The Journal of Organic Chemistry
DOI: 10.1021/acs.joc.6b02696

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