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Gene-OFF switches tool up synthetic biology

Researchers have developed two types of programmable repressor elements that can switch off the production of an output protein in synthetic biology circuits by up to 300-fold in response to almost any triggering nucleotide sequence. The researchers combined up to four repressor elements in universal NAND (NOT-AND) and NOR (NOT-OR) gates in complex molecular logic boards.

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Novel nanostructures could make smartphones more efficient

Researchers are pushing the boundaries of the laws of physics, developing nanocomposite materials and nanoelectronic circuits to greatly improve energy, thermal and computing performance. This could make smartphones and other electronics more efficient and boost the potential of solar power.

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World-leading microscopes take candid snapshots of atoms in their ‘neighborhoods’

Scientists use powerful 4D-STEM electron microscopy technique to map out the best atomic ‘hangouts’ in high-performance materials.

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An ‘anti-aging’ gene therapy trial in dogs begins, and Rejuvenate Bio hopes humans will be next

The startup, spun out of George Church’s lab, has tested an experimental therapy that treats four age-related diseases in mice

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Genetic glitch may forestall Alzheimer’s

Researchers aim to develop new therapies that mimic the mutation’s effects

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Being bullied? Here’s what to do

Recognize what’s really going on, enlist support, and be kind to yourself

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Your dog might be hiding its true colors

New research shows that some breeds of dogs have hidden coat colors — and in some cases, other traits — that have been lurking all along.

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Red deer are evolving to give birth earlier in a warming climate

Red deer living on the Isle of Rum, on the west coast of Scotland, have been giving birth earlier and earlier since the 1980s, at a rate of about three days per decade. New results now show that genetic change due to natural selection is partly contributing to the change: red deer are evolving.

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Potential drug targets for glioblastoma identified

Researchers have identified 10 tumor-specific potential drug targets for the brain tumor glioblastoma.

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Perovskite solar cells get an upgrade

Materials scientists find inorganic compounds quench defects in perovskite-based solar cells and expand their tolerance of light, humidity and heat.

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